Pregnancy Risk Category C
How supplied
Cream: 0.025%, 0.05%, 0.1%
Gel: 0.01%, 0.025%
Solution: 0.05%
Action
Inhibits comedones by increasing epidermal cell mitosis and turnover.
Indications & dosage
Acne vulgaris--
Adults and children: clean affected area and lightly apply once daily h.s.
Adjunct therapy to skin care and sun avoidance program--
Adults: apply to affected area once
daily h.s.
Adverse reactions
Skin: feeling of warmth, slight stinging, local erythema, peeling, chapping, swelling, blistering, crusting, temporary hyperpigmentation or hypopigmentation.
Interactions
Drug-drug. Topical drugs containing resorcinol, salicylic acid, or sulfur: increased risk of skin irritation. Don't use together.
Topical minoxidil or photosensitizing drugs: increased risk of skin irritation. Don't use together.
Drug-lifestyle. Abrasive cleansers, medicated cosmetics, skin preparations containing alcohol: increased risk of skin irritation. Don't use together.
Sun exposure: increased photosensitivity reactions. Avoid prolonged or unprotected exposure to sun.
Effects on diagnostic tests
None reported.
Contraindications
Contraindicated in patients with hypersensitivity to drug or its components.
Nursing considerations
Patient teaching
*Liquid contains alcohol. **May contain tartrazine. †Canada ‡Australia §U.K. OTCOver the counter
Reactions may be common, uncommon, life-threatening, or COMMON AND LIFE-THREATENING