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latanoprost
Xalatan

Pregnancy Risk Category C

How supplied
Ophthalmic solution:
0.005% (50 mcg/ml)

Action
Exact mechanism unknown. Believed to increase outflow of aqueous humor, thereby lowering intraocular pressure (IOP).

Indications & dosage
Increased IOP in patients with ocular hypertension or open-angle glaucoma who are intolerant of other IOP-lowering drugs or insufficiently responsive to other IOP-lowering drugs-

Adults:
1 drop in conjunctival sac of affected eye once daily in the evening.

Adverse reactions
CV:
angina pectoris, chest pain.
EENT:
blurred vision, burning, stinging, conjunctival hyperemia, foreign body sensation, itching, increased brown pigmentation of the iris, dry eye, punctate epithelial keratopathy, lid crusting or edema, lid discomfort, excessive tearing, eye pain, photophobia.
Musculoskeletal:
muscle, joint, or back pain.
Respiratory:
upper respiratory tract infection.
Skin:
rash, allergic skin reaction.
Other:
cold or flu.

Interactions
Drug-drug.
Eyedrops containing thimerosal: precipitation occurs when mixed with latanoprost. If used concomitantly, administer at least 5 minutes apart.

Effects on diagnostic tests
None reported.

Contraindications
Contraindicated in patients with hypersensitivity to drug, benzalkonium chloride, or other components of drug.

Nursing considerations

Patient teaching

*Liquid contains alcohol. **May contain tartrazine.  †Canada  ‡Australia  §U.K.  OTCOver the counter
Reactions may be common, uncommon, life-threatening, or COMMON AND LIFE-THREATENING

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