Pregnancy Risk Category C
How supplied
Cream: 2%
Shampoo: 2%
Action
Unknown. An imidazole that probably inhibits yeast growth by altering the permeability of the cell membrane.
Indications & dosage
Tinea corporis, tinea cruris, tinea pedis, tinea versicolor due to susceptible organisms; seborrheic dermatitis; cutaneous candidiasis--
Adults: cover affected and immediate surrounding area once daily for at least 2 weeks; for seborrheic dermatitis, apply b.i.d. for 4 weeks. Patients with tinea pedis need 6 weeks of treatment. When using shampoo, wet hair, lather, and massage for 1 minute. Rinse and repeat, but leave drug on scalp for 3 minutes before rinsing. Shampoo twice weekly for 4 weeks, with at least 3 days between shampoos and then intermittently, p.r.n., to maintain control.
Adverse reactions
Hepatic: transient elevations in AST, ALT, and alkaline phosphatase levels.
Metabolic: transient alterations in serum cholesterol and triglyceride levels.
Skin: severe irritation, pruritus, stinging with cream use; increase in normal hair loss, irritation, abnormal hair texture, scalp pustules, pruritus, oiliness or dryness of hair and scalp with shampoo use.
Interactions
Drug-drug. Topical corticosteroids: may cause increased absorption of corticosteroid. Avoid concomitant use.
Effects on diagnostic tests
None reported.
Contraindications
Contraindicated in patients with hypersensitivity to drug or its components.
Nursing considerations
Patient teaching
*Liquid contains alcohol. **May contain tartrazine. †Canada ‡Australia §U.K. OTCOver the counter
Reactions may be common, uncommon, life-threatening, or COMMON AND LIFE-THREATENING